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| 카탈로그 번호 | HY302016 |
|---|---|
| 설명 |
Grisnilimab (HY302016) is a research-grade recombinant antibody targeting CD7. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG2a-Lambda |
| 발현 시스템 | Mammalian cells |
| 타겟 | GP40, CD7, T-cell surface antigen Leu-9, T-cell leukemia antigen, TP41, T-cell antigen CD7 |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P09564 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | WT1, 2367001-70-3 |
| 배경 | T-cell antigen CD7 is a ~25 kDa protein. Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels. 1. Rabinowich, H. et al. (1994) Journal of immunology (Baltimore, Md. : 1950) 152, 517-26. PMID: 7506726 2. Lyman, SD. et al. (2000) The Journal of biological chemistry 275, 3431-7. PMID: 10652336 3. Carrel, S. et al. (1991) European journal of immunology 21, 1195-200. PMID: 1709867 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507) |
Detects Human CD7 in indirect ELISAs.
SEC-HPLC detection for Research Grade Grisnilimab.
SDS-PAGE for Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)
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