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| 카탈로그 번호 | HF990016 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Functional assay, Research in vivo |
| 이소타입 | Recombinant human Insulin analogue |
| 생물학적 활성 | Insulin cattle is the two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has often been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 ug/mL of medium [1]. in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells. |
| 발현 시스템 | Mammalian cells |
| 타겟 | INS, Insulin |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Purified by Nickel column. |
| 등록번호 | P01308 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Insulin is a ~11 kDa protein. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| 참고 문헌 | 1. Yousefi R, et al. Aspirin-mediated acetylation induces structural alteration and aggregation of bovine pancreaticinsulin. J Biomol Struct Dyn. 2016;34(2):362-75. [HF990016] |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
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