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Anti-Human CD133 Recombinant Antibody (SAA0050), APC (HT495137)

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개요
카탈로그 번호HT495137
종 반응성Human
응용 분야FCM
숙주 종Human
클론성Monoclonal
이소타입IgG1
클론 IDSAA0050
접합APC
타겟 PROML1, PROM1, Prominin-1, Antigen AC133, CD133, Prominin-like protein 1
내독소 수준 Please contact with the lab for this information.
관련 제품 Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
등록번호 O43490
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Store at 4°C for 12 months. Protect from light. Do not freeze.
배경

Prominin-1 (CD133/PROM1) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617
2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439
참고사항 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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