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| 카탈로그 번호 | HY436013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | WB | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | 2A2 | ||||
| 타겟 | APP secretase, CPSB, Cathepsin B, Cathepsin B1, CTSB, APPS | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P07858 | ||||
| RRID | Anti-Human CTSB Antibody (2A2) (abinScience Cat# HY436013, RRID:AB_3728963) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Cathepsin B (CTSB) is a ~37 kDa protein. Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. 1. Guo, R. et al. (2002) Biochemical and biophysical research communications 297, 38-45. PMID: 12220505 2. Ritonja, A. et al. (1985) FEBS letters 181, 169-72. PMID: 3972105 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307) |
SDS-PAGE for Anti-Human CTSB Antibody (2A2).
Flow-cytometry using FITC anti-human CTSB antibody. HepG-2 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CTSB monoclonal antibody (Catalog: HY436013, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
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