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| 카탈로그 번호 | HT495023 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | FCM, ICC, IF, IHC, WB | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | scFv-His | ||||
| 클론 ID | AC133/1 | ||||
| 타겟 | Prominin-1, Antigen AC133, Prominin-like protein 1, CD133, PROM1, PROML1, MSTP061 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | O43490 | ||||
| RRID | Anti-Human Glycosylated CD133/PROM1 Antibody (AC133/1) (abinScience Cat# HT495023, RRID:AB_3729293) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Prominin-1 (Glycosylated CD133) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. 1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617 2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human Glycosylated CD133/PROM1 Antibody (AC133/1)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
