Complete Workflow Screening → Confirmatory → Titer
Dual Formats Bridging ELISA & ECL (high dynamic range)
Acid Dissociation Disrupts ADA–drug complexes
Tolerance Data Drug/target interference, MRD guidance
Lot-Specific Docs Curves, precision, specificity
Binding-ADA detection for biologics and Fc-fusion research
Workflow training, method development and technology transfer (RUO)
Bridging to PK/NAb studies via matched reagents
What is the difference between binding-ADA and neutralizing-ADA?
Binding-ADA detects antibodies that bind the drug (regardless of function); NAb assesses whether binding neutralizes drug activity. NAb studies typically follow confirmed ADA positives.
When should I apply acid dissociation?
Use when residual drug may mask ADA in immune complexes. Acid dissociation disrupts complexes to improve detection, followed by neutralization per protocol.
How is confirmatory testing interpreted?
Co-incubate samples with free drug and calculate signal inhibition. Samples meeting the predefined inhibition threshold are confirmed true positives.
RUO disclaimer
All kits are for Research Use Only (RUO) and not intended for diagnostic or therapeutic use.
中文
English
