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InVivo Plus Antibodies

abinScience InVivo Plus antibodies are functional-grade reagents prepared for animal research—azide-free, low endotoxin, sterile-filtered and aggregation-tested (e.g., SEC-HPLC/DLS). Each lot includes a CoA with concentration, endotoxin (LAL), purity, and sterility/bioburden checks, plus recommended handling and dosing notes. Formats include IgG and F(ab')2, optional Fc-engineered variants, and carrier-protein-free buffers. RUO

Why Researchers Choose abinScience

Animal-Ready Buffer Azide-free, glycerol-free, carrier-free
Low Endotoxin LAL-tested, 0.22 μm sterile-filtered
Aggregation Control SEC-HPLC/DLS, high purity SDS-PAGE
Format Flexibility IgG, F(ab')2, Fc-engineered, isotypes
Lot-Specific QC CoA, handling, global cold-chain

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Selection & Handling Guide

  1. Mechanism: Choose blocking vs. depleting vs. neutralizing; verify clone MoA and target expression in your model.
  2. Format & Fc: Select IgG for Fc-dependent functions; F(ab')2 to avoid FcγR engagement; consider Fc-silenced/effector-enhanced variants as needed.
  3. Dose & Route: Plan mg/kg and schedule per literature/model; common routes include i.p., i.v., s.c. (follow IACUC/ethics guidelines).
  4. Buffer & Endotoxin: Confirm azide-free, carrier-free buffer and low endotoxin on the lot CoA; avoid repeated freeze–thaw (aliquot if needed).
  5. Controls: Include matched in vivo isotype controls and vehicle controls; monitor body weight and clinical scores per protocol.

Documents & QC

Lot-specific CoA: concentration, purity, endotoxin, sterility/bioburden
SEC-HPLC/DLS aggregation profile; SDS-PAGE image
Storage, stability, and thaw/aliquot instructions

FAQs

What makes an “InVivo Plus” antibody different from standard lab grade?

InVivo Plus products are azide-free, low endotoxin, sterile-filtered and aggregation-controlled, with carrier-free buffers and lot-level QC tailored to animal research workflows.

Can I use InVivo Plus antibodies for diagnostics or therapy?

No. All products are for Research Use Only (RUO), not for diagnostic or therapeutic procedures.

Should I choose IgG or F(ab')2?

Use IgG when Fc effector function is desired (e.g., depletion via ADCC/ADCP); choose F(ab')2 to avoid FcγR interactions in models sensitive to Fc-mediated effects.

What endotoxin level is recommended?

Select low-endotoxin lots as stated on the CoA and consistent with your protocol; always report and control endotoxin alongside dose and route.

Any handling tips?

Thaw gently on ice, mix by slow inversion, and prepare single-use aliquots to avoid freeze–thaw cycles. Use sterile technique and appropriate PPE.

Naming note

“InVivo Plus” here denotes abinScience’s internal grade specification for animal research antibodies.

24 product results for "InVivo Plus"

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  • Product types
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    Antibodies (24)
  • Target
    0 selected
    IFNAR1 (1)
    CD40/TNFRSF5 (1)
    Ly6g/Ly-6G.1 (1)
    IgG2b (4)
    CD279/PD-1 (2)
    IL17A (1)
    IgG1 (5)
    CD152/CTLA4 (1)
    CD161/KLRB1 (1)
    CD4 (1)
    PDL1 (1)
    CD274/PD-L1 (1)
    CD137/4-1BB (1)
    IgG2a (1)
    IgG (1)
    CD8a/Lyt2 (1)
  • Species
    0 selected
    Mouse (12)
  • Applications
    0 selected
    in vivo PD-L1 blockade (1)
    in vivo blockade (1)
    in vivo MDSC depletion (1)
    in vivo CTLA-4 neutralization (1)
    in vitro PD-L1 blockade (1)
    IHC (3)
    Neutralization (3)
    in vivo intra-tumoral regulatory T cell depletion (1)
    in vivo NK cell depletion (2)
    IF (4)
    ELISA (1)
    FCM (19)
    in vivo CD4+ T cell depletion (1)
    IHC-F (1)
    in vivo 4-1BB stimulation (1)
    Isotype Control (11)
    in vivo blocking of PD-1/PD-L signaling (1)
    WB (6)
    in vitro 4-1BB stimulation (1)
    in vivo CD8+ T cell depletion (1)
    in vivo IFNAR-1 blockade (1)
    FCMin vivo CD40 activation (1)
    Western blot (1)
    in vitro IFNAR-1 blockade (1)
    in vitro B cell stimulation/activation (1)
    in vivo neutrophil depletion (1)
    In vivo Control (8)
  • Reactivity
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    Mouse (3)
  • Host species
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    Mouse (12)
    Rabbit (1)
    Rat (11)
  • Clonality
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    Monoclonal (24)
  • Conjugate
    0 selected
    Unconjugated (24)

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