| Catalog No. | AF004024 |
|---|
| Applications | ELISA |
|---|
| Host species | Rabbit |
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| Isotype | IgG |
|---|
| Clonality |
Polyclonal |
| Immunogen |
Panitumumab |
| Target |
Rabbit polyclonal to Vectibix. |
| Specificity |
The product is specific for Panitumumab. This antibody serves as an excellent positive control for Panitumumabb immunogenicity (ADA) assays. |
| Endotoxin level |
Please contact with the lab for this information. |
| Purification |
Purified by antigen affinity column. |
| Accession |
CAS: 339177-26-3 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Product Usage Information |
| Application |
Dilution |
| ELISA |
1:5000-1:20000 |
| IHC |
1:50-1:500 |
| WB |
1:500-1:2000 |
|
|---|
| Stability and Storage |
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
| Background | Panitumumab with trade name Vectibix, is an FDA-approved drug for the treatment of patients with EGFR-expressing metastatic colorectal carcinoma with non-mutated (wild-type) KRAS after failure of fluoropyrimidine-, oxaliplatin- and irinotecan-containing chemotherapy regimens. It is a human monoclonal antibody. Panitumumab binds to the human EGF receptor (EGFR), preventing binding of activating ligands, such as the EGF and transforming growth factor-α. Antibodysystem Anti-Panitumumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Panitumumab.
• Multiplexed evaluation of a cell-based assay for the detection of antidrug neutralizing antibodies to panitumumab in human serum using automated fluorescent microscopy., PMID:20508254
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|---|
| Note |
For research use only. |
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