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Anti-Etanercept Polyclonal Antibody (AF879044)

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Overview
Catalog No.AF879044
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
ClonalityPolyclonal
ImmunogenEtanercept
TargetRabbit polyclonal to Enbrel.
SpecificityThe product is specific for Etanercept. This antibody serves as an excellent positive control for Etanercept immunogenicity (ADA) assays.
PurificationPurified by antigen affinity column.
Accession 185243-69-0
FormLiquid
Storage buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and StorageThe product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundEtanercept with trade name Enbrel, is an FDA-approved drug to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. Etanercept is a fusion protein made from the combination of two naturally occurring soluble human 75-kilodalton TNF receptors linked to an Fc portion of an IgG1. Etanercept treats autoimmune diseases by interfering with tumor necrosis factor-alpha (TNFα, a soluble inflammatory cytokine) by acting as a TNFα inhibitor.
NoteFor research use only.
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