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Anti-Ustekinumab Polyclonal Antibody (AB769014)

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Overview
Catalog No.AB769014
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen Ustekinumab
Target Rabbit polyclonal to Stelara.
Specificity The product is specific for Ustekinumab. This antibody serves as an excellent positive control for Ustekinumab immunogenicity (ADA) assays.
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession CAS: 815610-63-0
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundUstekinumab with trade name Stelara, is an FDA-approved drug to Crohn's disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis, targeting both interleukins (IL)-12 and IL-23. Ustekinumab is a fully human immunoglobulin G1 kappa mAb that binds to IL-12 and IL-23. Ustekinumab binds to the p40 subunit common to IL-12 and IL-23 and prevents their interaction with the IL-12 receptor β1 subunit of the IL-12 and IL-23 receptor complexes, thereby disrupting the proinflammatory pathway. Antibodysystem Anti-Ustekinumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Ustekinumab.
Note For research use only.
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