| Catalog No. | AW338014 |
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| Applications | ELISA |
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| Host species | Rabbit |
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| Isotype | IgG |
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| Clonality | Polyclonal |
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| Immunogen | Ramucirumab |
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| Specificity | The product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays. |
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| Purification | Purified by antigen affinity column. |
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| Accession | 947687-13-0 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
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| Stability and Storage | The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
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| Alternate Names | Rabbit polyclonal to REGN-10987. |
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| Background | Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells. |
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| Note | For research use only. |
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