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|---|---|
| Species reactivity | Human | 
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | 
| Host species | Human | 
| Isotype | IgG1-lambda | 
| Expression system | Mammalian Cells | 
| Clonality | Monoclonal | 
| Target | Extrinsic pathway inhibitor, Lipoprotein-associated coagulation inhibitor, TFPI, EPI, LACI, TFPI1, Tissue factor pathway inhibitor | 
| Endotoxin level | Please contact the lab for this information. | 
| Purity | >95% purity as determined by SDS-PAGE. | 
| Purification | Protein A/G purified from cell culture supernatant. | 
| Accession | P10646 | 
| Form | Liquid | 
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. | 
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. | 
| Alternate Names | PF-06741086, 1985638-39-8 | 
| Background | Befovacimab (BAY 1093884) is a fully human monoclonal IgG2 antibody able to bind to tissue factor pathway inhibitor (TFPI). Befovacimab can be used for haemophilia A/B research. | 
| Note | For research use only. Not suitable for clinical or therapeutic use. | 

SEC-HPLC detection for Research Grade Marstacimab.

Detects TFPI in indirect ELISAs.

Flow-cytometry using anti-human TFPI antibody. HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human TFPI monoclonal antibody (Catalog HY403036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

SDS-PAGE for Research Grade Marstacimab
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