| Catalog No. | JN043016 |
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| Species reactivity | Candida albicans |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Human |
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| Isotype | scFv-heavy-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | HSP90 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P46598 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | HSP90mab, Mycograb, 762260-74-2 |
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| Background | Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC).
• The HSP90 chaperone machinery., PMID:28429788
• The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease., PMID:30158430
• Hsp90: structure and function., PMID:22955504
• HSP90 multi-functionality in cancer., PMID:39148727
• HSP90 and Noncoding RNAs., PMID:37638805
• HSP90 mediates the connection of multiple programmed cell death in diseases., PMID:36335088
• Cytosolic Hsp90 Isoform-Specific Functions and Clinical Significance., PMID:36139005
• Hsp90: Bringing it all together., PMID:39889818
• Organelle-specific Hsp90 inhibitors., PMID:26195286
• Linking hsp90's role as an evolutionary capacitator to the development of cancer., PMID:34023771
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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