| Catalog No. | JN043016 |
|---|
| Species reactivity | Candida albicans |
|---|
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
|---|
| Host species | Human |
|---|
| Isotype | scFv-heavy-kappa |
|---|
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
HSP90 |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
P46598 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | HSP90mab, Mycograb, 762260-74-2 |
|---|
| Background | Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC).
• The HSP90 chaperone machinery., PMID:28429788
• The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease., PMID:30158430
• Hsp90: structure and function., PMID:22955504
• HSP90 multi-functionality in cancer., PMID:39148727
• HSP90 and Noncoding RNAs., PMID:37638805
• HSP90 mediates the connection of multiple programmed cell death in diseases., PMID:36335088
• Cytosolic Hsp90 Isoform-Specific Functions and Clinical Significance., PMID:36139005
• Hsp90: Bringing it all together., PMID:39889818
• Organelle-specific Hsp90 inhibitors., PMID:26195286
• Linking hsp90's role as an evolutionary capacitator to the development of cancer., PMID:34023771
|
|---|
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
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