Catalog No. | HS856086 |
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Species reactivity | Human |
Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
Host species | Humanized |
Isotype | VH-VH'-VH |
Expression system | Mammalian Cells |
Clonality | Monoclonal |
Target | CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17A, IL17A, CTLA8, IL-17, Interleukin-17A, IL17F, Interleukin-17F, IL-17F, Cytokine ML-1, ALB, Albumin |
Endotoxin level | Please contact the lab for this information. |
Purity | >95% purity as determined by SDS-PAGE. |
Purification | Purified by Nickel column. |
Accession | Q16552 & Q96PD4 & P02768 |
Form | Liquid |
Storage buffer | 30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80 |
Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names | Bispecific, Trivalent, M-1095, MSB-0010841, 1414386-05-2 |
Background | Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis. |
Note | For research use only. Not suitable for clinical or therapeutic use. |
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