| Catalog No. | HP572016 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized(Lama/glama) |
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| Isotype | VH-VH' |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAM-TS 5, ADAM-TS5, ADAMTS-5, EC:3.4.24.-, A disintegrin and metalloproteinase with thrombospondin motifs 11, ADAM-TS 11, ADAMTS-11, ADMP-2, Aggrecanase-2, ADAMTS5, ALB, Albumin |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | Q9UNA0 & P02768 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | Bispecific, M-6495, 2254082-79-4 |
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| Background | Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life. |
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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