| Catalog No. | HW541046 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Isotype | Human interleukin-15/IL-15 fragment variant fused via peptide linker to a human IgG1 C-terminal Fc fragment disulfide bridge with human interleukin-15 receptor subunit alpha fragment fused via a peptide linker to a human immunoglobulin G1 Fc fragment. |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | IL15, IL-15, Interleukin-15, IL-15 receptor subunit alpha, sIL-15R-alpha, IL-15RA, CD215, sIL-15 receptor subunit alpha, Interleukin-15 receptor subunit alpha, IL-15R-alpha, sIL-15RA, IL15RA |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Purified by nickel column chromatography. |
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| Accession | P40933 & Q13261 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | CAS:2736449-62-8 |
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| Background | Efbalropendekin Alfa (XmAb24306) is an IL-15/IL-15 receptor alpha complex fused to a heterodimeric Fc domain (IL15/IL15Rα-Fc). Efbalropendekin Alfa increases direct and antibody-dependent cellular cytotoxicity (ADCC)-mediated human natural killer (NK) cell cytotoxicity in vitro. |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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