| Catalog No. | HF802016 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | IgG1-kappa |
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| Expression system | Mammalian Cells |
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| Species | Human |
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| Clonality | Monoclonal |
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| Target | IL1F1, Interleukin-1 alpha, IL1A, Hematopoietin-1, IL-1 alpha |
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| Endotoxin level | Please contact with the lab for this information. |
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| Purity | >95% as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P01583 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| Alternate Names | MABp1, Xilonix, CAS: 1401965-15-8, CA-18C3, CV-18C3, RA-18C3, T2-18C3 |
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| Background | Vilamakitug is an anti-PDCD1 human IgG4 κ monoclonal antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
• The Interleukin-1 Family., PMID:27734407
• Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis., PMID:33200890
• Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity., PMID:39577420
• Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure., PMID:31836429
• Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance., PMID:33037057
• Parenchyma-stromal interleukin-1 alpha and interleukin-6 overexpressions in ameloblastoma correlate with the aggressive phenotype., PMID:31901915
• IL-1 family cytokines in cardiovascular disease., PMID:29198612
• The interactions between interleukin-1 family genes: IL1A, IL1B, IL1RN, and obesity parameters., PMID:35139823
• Association between interleukin-1 alpha rs1800587 polymorphism and rheumatoid arthritis: A meta-analysis., PMID:33950757
• The Association between TNF-alpha, IL-1 alpha and IL-10 with Alzheimer's Disease., PMID:33256580
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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