| Catalog No. | HY038016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Chimeric |
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| Isotype | IgG4-kappa |
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| Expression system | Mammalian Cells |
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| Species | Human |
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| Clonality | Monoclonal |
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| Target | Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14 |
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| Endotoxin level | Please contact with the lab for this information. |
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| Purity | >95% as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P08571 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| Alternate Names | 28C5, termed IC14, CAS: 2417175-94-9 |
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| Background | Atibuclimab, is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab can be used for the research of amyotrophic lateral sclerosis. Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist. |
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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