| Catalog No. | HV702046 |
|---|
| Species reactivity | Human |
|---|
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
|---|
| Host species | Humanized |
|---|
| Isotype | half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3 |
|---|
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
CD278, ICOS, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, AILIM, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279 |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
Q9Y6W8 & Q15116 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | Bispecific, XmAb-23104, 2329669-80-7 |
|---|
| Background | Izuralimab is a bispecific IgG1 antibody targeting inducible T-cell costimulator (ICOS/CD278) and PD-1.
|
|---|
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
