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Anti-Certolizumab Polyclonal Antibody (AF879054)

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Overview
Catalog No.AF879054
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
ClonalityPolyclonal
ImmunogenCertolizumab
TargetCertolizumab
SpecificityThe product is specific for Certolizumab. This antibody serves as an excellent positive control for Certolizumab immunogenicity (ADA) assays.
PurificationPurified by antigen affinity column.
Accession 428863-50-7
FormLiquid
Storage buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and StorageThe product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundCertolizumab is a Fab fragment of a monoclonal antibody to human tumor necrosis factor alpha (TNFα) which has potent antiinflammatory activity and is used in the therapy of severe rheumatoid arthritis and inflammatory bowel disease. Antibodysystem Anti-Certolizumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Certolizumab.
• Certolizumab pegol, abatacept, tocilizumab or active conventional treatment in early rheumatoid arthritis: 48-week clinical and radiographic results of the investigator-initiated randomised controlled NORD-STAR trial., PMID:37423647
• Certolizumab Pegol: A Review in Moderate to Severe Plaque Psoriasis., PMID:32207094
• Certolizumab Pegol in Plaque Psoriasis: Considerations for Pregnancy., PMID:33769772
• Certolizumab treatment of localized pyoderma gangrenosum in a pregnant patient., PMID:37905433
• Certolizumab pegol for hidradenitis suppurativa: Case report and literature review., PMID:33135826
• Certolizumab pegol for induction of remission in Crohn's disease., PMID:31476018
• ACG Clinical Guideline: Management of Crohn's Disease in Adults., PMID:29610508
• [Certolizumab]., PMID:31208736
• Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation., PMID:27140438
• Certolizumab pegol for the treatment of psoriatic arthritis and plaque psoriasis., PMID:31917928
NoteFor research use only.
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