| Catalog No. | HX930016 |
|---|
| Species reactivity | Human |
|---|
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
|---|
| Host species | Humanized |
|---|
| Isotype | IgG1-kappa |
|---|
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
ROR2, Neurotrophic tyrosine kinase, receptor-related 2, NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2 |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
Q01974 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | BA302, 2460399-44-2 |
|---|
| Background | Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC.
• A proteogenomic portrait of lung squamous cell carcinoma., PMID:34358469
• WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth., PMID:36622276
• ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma., PMID:38975886
• Robinow syndrome., PMID:12011143
• Ror2 as a therapeutic target in cancer., PMID:25614331
• Prognostic value of receptor tyrosine kinase-like orphan receptor (ROR) family in cancer: A meta-analysis., PMID:31174180
• Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis., PMID:32951408
• The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis., PMID:23233346
• Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer., PMID:36463543
• Purification and characterization of the extracellular region of human receptor tyrosine kinase like orphan receptor 2 (ROR2)., PMID:30826310
|
|---|
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
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