Research Grade Duligotuzumab (HB116036)

Name: Research Grade Duligotuzumab
Brand: abinScience
SKU: HB116036
Price: 326 USD
Availability: InStock

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Spec:

100ug
1mg

Number:

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Datasheet

Overview

Catalog No.	HB116036
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG1-kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P21860
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	MEHD7945A, RG-7597, 1314238-96-4
Background	Nezutatug is an anti-HER3 antibody, and used for cancer research.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Duligotuzumab.
SDS-PAGE

SDS-PAGE for Research Grade Duligotuzumab.
Flow CytoMetry

Flow-cytometry using APC anti-human ERBB3 antibody. MCF-7 cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human ERBB3 monoclonal antibody (Catalog: HB116036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using PE anti-human ERBB3 antibody. MCF-7 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human ERBB3 monoclonal antibody (Catalog: HB116036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using FITC anti-human ERBB3 antibody. HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human ERBB3 monoclonal antibody (Catalog: HB116036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using anti-human ERBB3 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human ERBB3 monoclonal antibody (Catalog: HB116036) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet

Research Grade Duligotuzumab.pdf

Recombinant Proteins

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Research Grade Duligotuzumab (HB116036)

Overview

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Datasheet

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