Anti-Human SNW1 Polyclonal Antibody (HC408014)

Name: Anti-Human SNW1 Polyclonal Antibody
Brand: abinScience
SKU: HC408014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HC408014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SNW1 (Ser14-Glu201).

Target

SNW1, SKIP, Ski-interacting protein, Nuclear receptor coactivator NCoA-62, SKIIP, Nuclear protein SkiP, SNW domain-containing protein 1

Purification

Purified by antigen affinity column.

Accession

Q13573

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

SNW domain-containing protein 1 (SNW1) is a ~61 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Required for the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. May recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.

1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638

2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346

3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human SNW1 polyclonal antibody at 1ug/mL on recombinant Human SNW1 (Catalog No. HC408012).

References

Datasheet

Anti-Human SNW1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SNW1 Polyclonal Antibody (HC408014)

Overview

Images

References

Datasheet

SDS

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