Anti-BAG5 Polyclonal Antibody (HP706014)

Name: Anti-BAG5 Polyclonal Antibody
Brand: abinScience
SKU: HP706014
Price: 168 USD
Availability: InStock

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Price(USD): $

Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.

HP706014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human BAG5 (Met1-Asp248).

Target

BAG5, KIAA0873, BAG-5, BAG family molecular chaperone regulator 5, Bcl-2-associated athanogene 5

Purification

Purified by antigen affinity column.

Accession

Q9UL15

RRID

Anti-BAG5 Polyclonal Antibody (abinScience Cat# HP706014, RRID:AB_3722879)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

BAG family molecular chaperone regulator 5 (BAG5) is a ~51 kDa protein. Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN.

1. Arakawa, A. et al. (2010) Structure (London, England : 1993) 18, 309-19. PMID: 20223214

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-BAG5 polyclonal antibody at 1ug/mL on recombinant BAG5 (Catalog No. HP706012).

References

Datasheet

Anti-BAG5 Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-BAG5 Polyclonal Antibody (HP706014)

Overview

Images

References

Datasheet

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