

| Catalog No. | VK762014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Hepatitis B virus | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant HBV C/Capsid protein (Met1-Val149). | ||||||||
| Target | core protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P03146, P0C6I2, P0C573, Q67876 | ||||||||
| RRID | Anti-HBV C/Capsid protein Polyclonal Antibody (abinScience Cat# VK762014, RRID:AB_3723086) |
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| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Capsid protein (HBcAg) is a ~21 kDa protein. Self assembles to form an icosahedral capsid. Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins. Entering capsids are transported along microtubules to the nucleus. Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta. Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-HBV C/Capsid protein polyclonal antibody at 1ug/mL on recombinant HBV C/Capsid protein (Catalog No. VK762012).
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