Anti-Human AMACR Polyclonal Antibody (HV443014)

Name: Anti-Human AMACR Polyclonal Antibody
Brand: abinScience
SKU: HV443014
Price: 168 USD
Availability: InStock

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Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.

HV443014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human AMACR (Ala2-Lys200).

Target

AMACR, Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase

Purification

Purified by antigen affinity column.

Accession

Q9UHK6

RRID

Anti-Human AMACR Polyclonal Antibody (abinScience Cat# HV443014, RRID:AB_3723333)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Alpha-methylacyl-CoA racemase (AMACR) is a ~42 kDa protein. Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs.

1. Ferdinandusse, S. et al. (2000) Nature genetics 24, 188-91. PMID: 10655068

2. Ferdinandusse, S. et al. (2000) Journal of lipid research 41, 1890-6. PMID: 11060359

3. Schmitz, W. et al. (1995) European journal of biochemistry 231, 815-22. PMID: 7649182

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human AMACR polyclonal antibody at 1ug/mL on recombinant Human AMACR (Catalog No. HV443022).

References

Datasheet