Anti-Human SNX3 Polyclonal Antibody (HT336014)

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT336014

Description

Anti-Human SNX3 Polyclonal Antibody (HT336014) is a rabbit polyclonal antibody detecting SNX3 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SNX3 (Met1-Ala162).

Target

SNX3, Protein SDP3, Sorting nexin-3

Purification

Purified by antigen affinity column.

Accession

O60493

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Sorting nexin-3 (SNX3) is a ~18 kDa protein. Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Can also bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC/VPS).

1. Harterink, M. et al. (2011) Nature cell biology 13, 914-923. PMID: 21725319

2. Harrison, MS. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 267-72. PMID: 24344282

3. McGough, IJ. et al. (2018) Nature communications 9, 3737. PMID: 30213940

4. Chua, RY. et al. (2013) Immunology 139, 30-47. PMID: 23237080

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human SNX3 polyclonal antibody at 1ug/mL on recombinant Human SNX3 (Catalog No. HT336012).

References

Datasheet

Anti-Human SNX3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SNX3 Polyclonal Antibody (HT336014)

Overview

Images

References

Datasheet

SDS

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