Anti-Human RGS10 Polyclonal Antibody (HT099014)

Name: Anti-Human RGS10 Polyclonal Antibody
Brand: abinScience
SKU: HT099014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT099014

Description

Anti-Human RGS10 Polyclonal Antibody (HT099014) is a rabbit polyclonal antibody detecting RGS10 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RGS10 (Ser31-Thr181).

Target

Regulator of G-protein signaling 10, RGS10, RGS10

Purification

Purified by antigen affinity column.

Accession

O43665

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Regulator of G-protein signaling 10 (RGS10) is a ~21 kDa protein. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein.

1. Tu, Y. et al. (1999) The Journal of biological chemistry 274, 38260-7. PMID: 10608901

2. Burgon, PG. et al. (2001) The Journal of biological chemistry 276, 32828-34. PMID: 11443111

3. Soundararajan, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6457-62. PMID: 18434541

4. Hunt, TW. et al. (1996) Nature 383, 175-7. PMID: 8774883

5. Tu, Y. et al. (1997) Science (New York, N.Y.) 278, 1132-5. PMID: 9353196

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human RGS10 polyclonal antibody at 1ug/mL on recombinant Human RGS10 (Catalog No. HT099012).

References

Datasheet

Anti-Human RGS10 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human RGS10 Polyclonal Antibody (HT099014)

Overview

Images

References

Datasheet

SDS

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