

| Catalog No. | VK505014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Influenza B virus (Flu B) Matrix protein M1 Polyclonal Antibody (VK505014) is a rabbit polyclonal antibody detecting matrix protein M1 in ELISA, IHC, WB.
Highlights
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| Species reactivity | Influenza B virus (B/Lee/1940) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Influenza B virus (Flu B) Matrix protein M1 (Met1-Leu248). | ||||||||
| Target | matrix protein M1, M1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P03489 | ||||||||
| RRID | Anti-Influenza B virus (Flu B) Matrix protein M1 Polyclonal Antibody (abinScience Cat# VK505014, RRID:AB_3725140) |
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| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Matrix protein 1 (Matrix protein M1) is a ~27 kDa protein. Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. | ||||||||
| Note | For research use only. |
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