Anti-Human FOS Antibody (N486/76) (HF569023)

Datasheet Share product Copy info

Price(USD): $

Spec:

20ug
50ug
100ug
1mg

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.

HF569023

Description

Anti-Human FOS Antibody (N486/76) [N486/76] (HF569023) is a mouse monoclonal antibody detecting FOS in IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

IHC, WB

Host species

Mouse

Isotype

IgG2a

Clone ID

N486/76

Clonality

Monoclonal

Target

FOS, G0S7, Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01100

RRID

Anti-Human FOS Antibody (N486/76) (abinScience Cat# HF569023, RRID:AB_3727065)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Protein c-Fos is a ~40 kDa protein. Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.

Note

For research use only.

Images