Anti-Human MTM1 Recombinant Antibody (SAA1671) (HC500013)

Name: Anti-Human MTM1 Recombinant Antibody (SAA1671)
Brand: abinScience
SKU: HC500013
Price: 196 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC500013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1671

Clonality

Monoclonal

Target

Myotubularin, Phosphatidylinositol-3, 5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase, MTM1, CG2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13496

RRID

Anti-Human MTM1 Antibody (SAA1671) (abinScience Cat# HC500013, RRID:AB_3727432)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Myotubularin (MTM1) is a ~69 kDa protein. Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture.

1. Taylor, GS. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8910-5. PMID: 10900271

2. Blondeau, F. et al. (2000) Human molecular genetics 9, 2223-9. PMID: 11001925

3. Schaletzky, J. et al. (2003) Current biology : CB 13, 504-9. PMID: 12646134

4. Tsujita, K. et al. (2004) The Journal of biological chemistry 279, 13817-24. PMID: 14722070

5. Cui, X. et al. (1998) Nature genetics 18, 331-7. PMID: 9537414

6. Hnia, K. et al. (2011) The Journal of clinical investigation 121, 70-85. PMID: 21135508

7. Gupta, VA. et al. (2013) PLoS genetics 9, e1003583. PMID: 23818870

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human MTM1 Antibody (SAA1671)

References

Datasheet

Anti-Human MTM1 Recombinant Antibody (SAA1671).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human MTM1 Recombinant Antibody (SAA1671) (HC500013)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us