Anti-JUNV Glycoprotein GP2 Antibody (VK721014)

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Overview
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Datasheet

Overview

Catalog No.

VK721014

Description

Anti-JUNV Glycoprotein GP2 Antibody (VK721014) is a rabbit polyclonal antibody detecting GP2 in ELISA, IHC, WB. Suitable for Machupo virus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Junin mammarenavirus, Machupo virus

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Junin mammarenavirus GP2 (Ala252-Asp424).

Target

GP2

Purity

>90%

Purification

Purified by antigen affinity column.

Accession

P26313

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

Pre-glycoprotein polyprotein GP complex, Pre-GP-C, Stable signal peptide, SSP, Glycoprotein G1, GP1, Glycoprotein G2, GP2, GPC

Background

Pre-glycoprotein polyprotein GP complex (GP2) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

1. York, J. et al. (2004) Journal of virology 78, 10783-92. PMID: 15367645

2. York, J. et al. (2006) Journal of virology 80, 7775-80. PMID: 16840359

Note

For research use only.

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References

Datasheet