Anti-SNV Glycoprotein Gn Antibody (SNV-42) (VK018013)

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50ug
100ug
1mg

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Overview
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Datasheet

Overview

Catalog No.

VK018013

Description

Anti-SNV Glycoprotein Gn Antibody (SNV-42) [SNV-42] (VK018013) is a human monoclonal antibody detecting Glycoprotein N in ELISA, Neutralization, BLI. Suitable for Sin Nombre Virus.

Highlights

●Multi-Application — Validated across multiple applications.

Species reactivity

Sin Nombre Virus

Applications

ELISA, Neutralization, BLI

Host species

Human

Isotype

IgG1, lambda

Clone ID

SNV-42

Clonality

Monoclonal

Target

Envelopment polyprotein, Glycoprotein N, Gn, Glycoprotein G1, GP

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q89905

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (Gn) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (Probable). This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif.

Note

For research use only.

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