Anti-Human GREM1 Antibody (SAA2524) (MT246013)

Datasheet Share product Copy info

Price(USD): $

Spec:

50ug
100ug
1mg

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.

MT246013

Description

Anti-Human GREM1 Antibody (SAA2524) [SAA2524] (MT246013) is a mouse monoclonal antibody detecting Grem1 in ELISA, FACS, Functional assay. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

Species reactivity

Mouse

Applications

ELISA, FACS, Functional assay

Host species

Mouse

Isotype

IgG1

Clone ID

SAA2524

Clonality

Monoclonal

Target

Cktsf1b1, Cysteine knot superfamily 1, BMP antagonist 1, Down-regulated in Mos-transformed cells protein, Drm, Grem1, Gremlin-1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O70326

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Gremlin-1 (GREM1) is a ~20 kDa protein. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis.

1. Khokha, MK. et al. (2003) Nature genetics 34, 303-7. PMID: 12808456

2. Michos, O. et al. (2004) Development (Cambridge, England) 131, 3401-10. PMID: 15201225

3. Pangas, SA. et al. (2004) The Journal of biological chemistry 279, 32281-6. PMID: 15133038

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Human GREM1 Antibody (SAA2524)

References

Datasheet

Anti-Human GREM1 Antibody (SAA2524).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human GREM1 Antibody (SAA2524) (MT246013)

Overview

Images

References

Datasheet

Quick access

Contact Us