Anti-Human EFTUD2 Polyclonal Antibody (HD650014)

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Datasheet

Overview

Catalog No.

HD650014

Description

Anti-Human EFTUD2 Polyclonal Antibody (HD650014) is a rabbit polyclonal antibody detecting EFTUD2. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human EFTUD2 (Thr661-Met972).

Target

116 kDa U5 small nuclear ribonucleoprotein component, EFTUD2, Elongation factor Tu GTP-binding domain-containing protein 2, KIAA0031, SNRP116, SNU114 homolog, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, hSNU114

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q15029

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) is a ~109 kDa protein. Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).

1. Oka, Y. et al. (2014) EMBO reports 15, 956-64. PMID: 25092792

2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346

3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770

4. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166

5. Zhan, X. et al. (2018) Science (New York, N.Y.) 359, 537-545. PMID: 29301961

6. Zhang, X. et al. (2018) Cell research 28, 307-322. PMID: 29360106

7. Haselbach, D. et al. (2018) Cell 172, 454-464.e11. PMID: 29361316

8. Zhan, X. et al. (2018) Cell research 28, 1129-1140. PMID: 30315277

9. Fica, SM. et al. (2019) Science (New York, N.Y.) 363, 710-714. PMID: 30705154

10. Liu, S. et al. (2006) RNA (New York, N.Y.) 12, 1418-30. PMID: 16723661

Note

For research use only

Images

References

Datasheet

Anti-Human EFTUD2 Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human EFTUD2 Polyclonal Antibody (HD650014)

Overview

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References

Datasheet

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