Anti-CALCB Polyclonal Antibody (HY449014)

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100ug

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Datasheet

Overview

Catalog No.

HY449014

Description

Anti-CALCB Polyclonal Antibody (HY449014) is a rabbit polyclonal antibody detecting CALCB in ELISA, IHC, WB. Suitable for Human, Ovis aries, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Ovis aries, Pelophylax ridibundus, Pig

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CALCB (Met1-Ala127).

Target

Calcitonin gene-related peptide II, CALCB, Calcitonin gene-related peptide 2, Beta-CGRP, CALC2, CGRP-II, Beta-type CGRP

Purification

Purified by antigen affinity column.

Accession

P10092

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Calcitonin gene-related peptide 2 (CALCB) is a ~13 kDa protein. CALCB/CGRP2 is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.

1. Kitamura, K. et al. (1992) Biochemical and biophysical research communications 185, 134-41. PMID: 1318039

2. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797

3. Petermann, JB. et al. (1987) The Journal of biological chemistry 262, 542-5. PMID: 3492492

Note

For research use only.

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