Anti-HGF Polyclonal Antibody (HB191014)

Datasheet Share product Copy info

Price(USD): $

Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.

HB191014

Description

Anti-HGF Polyclonal Antibody (HB191014) is a rabbit polyclonal antibody detecting HGF in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Cat, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Dog, Cat, Rat, Bos taurus

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HGF (Tyr28-Val209).

Target

SF, HPTA, Hepatopoietin-A, Hepatocyte growth factor, Scatter factor, HGF

Purification

Purified by antigen affinity column.

Accession

P14210

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Hepatocyte growth factor (HGF) is a ~83 kDa protein. Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation.

1. Tolbert, WD. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13264-9. PMID: 20624990

2. Stamos, J. et al. (2004) The EMBO journal 23, 2325-35. PMID: 15167892

3. Hashimoto, T. et al. (2010) The FEBS journal 277, 4888-900. PMID: 20977675

Note

For research use only.

Images