Anti-PTPRM Polyclonal Antibody (HB921014)

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50ug
100ug

Number:

Overview
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Datasheet

Overview

Catalog No.

HB921014

Description

Anti-PTPRM Polyclonal Antibody (HB921014) is a rabbit polyclonal antibody detecting PTPRM in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PTPRM (Thr1197-Ser1403).

Target

Protein-tyrosine phosphatase mu, R-PTP-mu, PTPRL1, PTPRM, Receptor-type tyrosine-protein phosphatase mu

Purification

Purified by antigen affinity column.

Accession

P28827

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Receptor-type tyrosine-protein phosphatase mu (PTPRM) is a ~163 kDa protein. Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation. Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function.

1. Zondag, GC. et al. (2000) The Journal of biological chemistry 275, 11264-9. PMID: 10753936

2. Aricescu, AR. et al. (2007) Science (New York, N.Y.) 317, 1217-20. PMID: 17761881

3. Kim, WK. et al. (2011) Molecular biology of the cell 22, 4883-91. PMID: 21998202

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-PTPRM polyclonal antibody at 1ug/mL on recombinant PTPRM (Catalog No. HB921012).

References

Datasheet

Anti-PTPRM Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-PTPRM Polyclonal Antibody (HB921014)

Overview

Images

References

Datasheet

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