Anti-Human Kappa Antibody (HP6156) (HB980107)

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Overview

Catalog No.	HB980107
Description	Anti-Human Kappa Antibody (HP6156) [HP6156] (HB980107) is a mouse monoclonal antibody detecting Immunoglobulin kappa constant in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1
Clone ID	HP6156
Clonality	Monoclonal
Target	Ig kappa chain C region EU, Ig kappa chain C region, Ig kappa chain C region ROY, Immunoglobulin kappa constant, IGKC, Ig kappa chain C region TI, Ig kappa chain C region OU, Ig kappa chain C region CUM, Ig kappa chain C region AG
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P01834
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Immunoglobulin kappa constant (Kappa Chain) is a ~11 kDa protein. Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
Note	For research use only.

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Datasheet

Anti-Human Kappa Antibody (HP6156).pdf

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Anti-Human Kappa Antibody (HP6156) (HB980107)

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Datasheet

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