

| Catalog No. | HY592117 |
|---|---|
| Description |
Anti-Human CD63/LAMP3 Antibody (MOF11), FITC [MOF11] (HY592117) is a human monoclonal antibody detecting CD63 in ELISA, FCM, WB. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, FCM, WB |
| Host species | Human |
| Isotype | IgG1 |
| Clone ID | MOF11 |
| Conjugation | FITC |
| Clonality | Monoclonal |
| Target | Ocular melanoma-associated antigen, TSPAN30, CD63 antigen, LAMP-3, Tetraspanin-30, OMA81H, Lysosomal-associated membrane protein 3, Tspan-30, Granulophysin, MLA1, Melanoma-associated antigen ME491, CD63, RHC37601 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P08962 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | CD63 antigen (LAMP3) is a ~25 kDa protein. Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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