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Anti-Human CD325/CDH2 Antibody (E4#), FITC (HB862317)

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Overview

Catalog No.	HB862317
Description	Anti-Human CD325/CDH2 Antibody (E4#), FITC [E4#] (HB862317) is a mouse monoclonal antibody detecting CD325 in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a
Clone ID	E4#
Conjugation	FITC
Clonality	Monoclonal
Target	N-cadherin, CDH2, Cadherin-2, CD325, CDw325, Neural cadherin, CDHN, NCAD
Endotoxin level	Please contact with the lab for this information.
Accession	P19022
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Cadherin-2 (CD325/CDH2) is a ~99 kDa protein. Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells. Required for proper neurite branching.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human CD325/CDH2 Antibody (E4#), FITC.pdf

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Anti-Human CD325/CDH2 Antibody (E4#), FITC