Anti-Human TMEFF1 Antibody (30C10), FITC (HP664117)

Datasheet Share product Copy info

Price(USD): $

Spec:

50T
100T

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.	HP664117
Description	Anti-Human TMEFF1 Antibody (30C10), FITC [30C10] (HP664117) is a mouse monoclonal antibody detecting TMEFF1 in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	30C10
Conjugation	FITC
Clonality	Monoclonal
Target	C9orf2, H7365, TMEFF1, TR-1, Transmembrane protein with EGF-like and one follistatin-like domain, Tomoregulin-1
Endotoxin level	Please contact with the lab for this information.
Accession	Q8IYR6
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Tomoregulin-1 (TMEFF1) is a ~40 kDa protein. Neuron-specific restriction factor that prevents herpes simplex virus 1 (HHV-1) infection in the brain by blocking viral entry. Also able to restrict herpes simplex virus 2 (HHV-2) infection, although to a lesser extent. Acts by preventing the association between the viral glycoprotein D (gD) and its cell surface receptor NECTIN1, thereby inhibiting fusion of the virus and the cell membrane. Also able to prevent the association between the viral glycoprotein B (gB) and MYH9/NMMHC-IIA and MYH10/NMMHC-IIB receptors. May be a tumor suppressor in brain cancers. 1. Dai, Y. et al. (2024) Nature 632, 383-389. PMID: 39048823 2. Chan, YH. et al. (2024) Nature 632, 390-400. PMID: 39048830 3. Gery, S. et al. (2003) Oncogene 22, 2723-7. PMID: 12743596
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

References

Datasheet

Anti-Human TMEFF1 Antibody (30C10), FITC.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TMEFF1 Antibody (30C10), FITC (HP664117)

Overview

Images

References

Datasheet

Quick access

Contact Us