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Anti-Mouse CD11b/ITGAM Antibody (M1/70), APC (MY474337)

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Overview

Catalog No.	MY474337
Description	Anti-Mouse CD11b/ITGAM Antibody (M1/70), APC [M1/70] (MY474337) is a rat monoclonal antibody detecting ITGAM in FCM. Suitable for Human and Mouse. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human, Mouse
Applications	FCM
Host species	Rat
Isotype	IgG2b, kappa
Clone ID	M1/70
Conjugation	APC
Clonality	Monoclonal
Target	CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, ITGAM, CD11b, CD11 antigen-like family member B, Integrin alpha-M, CR3A, CD11B, Neutrophil adherence receptor
Endotoxin level	Please contact with the lab for this information.
Accession	P05555
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain. 1. Wakselman, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 8138-43. PMID: 18685038
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Mouse CD11b/ITGAM Antibody (M1/70), APC.pdf

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Anti-Mouse CD11b/ITGAM Antibody (M1/70), APC