

| Catalog No. | HB135147 |
|---|---|
| Description |
Anti-Human CD155/PVR Antibody (7D4), PerCP [7D4] (HB135147) is a mouse monoclonal antibody detecting CD155 in FCM. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG1, kappa |
| Clone ID | 7D4 |
| Conjugation | PerCP |
| Clonality | Monoclonal |
| Target | Nectin-like protein 5 receptor, CD155, PVR, PVS, NECL-5 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P15151 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Poliovirus receptor (CD155/PVR) is a ~45 kDa protein. Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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