Anti-Human IgE/IGHE Recombinant Antibody (8D6), PE (HV064227)

Name: Anti-Human IgE/IGHE Recombinant Antibody (8D6), PE
Brand: abinScience
SKU: HV064227
Price: 290 USD
Availability: InStock

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Overview

Catalog No.	HV064227
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a
Clone ID	8D6
Conjugation	PE
Clonality	Monoclonal
Target	Ig epsilon chain C region, IGHE, Ig epsilon chain C region ND, Immunoglobulin heavy constant epsilon
Endotoxin level	Please contact with the lab for this information.
Accession	P01854
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Immunoglobulin heavy constant epsilon (IgE/IGHE) is a ~59 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.