Itolizumab ELISA Kit (DB797018)

Overview
Images
References
Datasheet

Overview

Catalog No.	DB797018
Description	Itolizumab ELISA Kit (DB797018) — Quantitative sandwich ELISA for Itolizumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml. Highlights ●Sandwich Format — High specificity, reliable quantification. ●High Sensitivity — Optimized for low-abundance target detection. ●Ready-to-Use — Complete kit with pre-coated plates included.
Sample type	Plasma, Serum
Sensitivity	0.156 μg/ml
Range	0.31-5 μg/mL
Accession	P30203
Applications	ELISA
Detection method	Colorimetric
Assay type	Quantitative
Recovery	80-120%
Shipping	2-8 ℃
Stability and Storage	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications	Itolizumab
Alternate Names	T1h, 1116433-11-4
Background	T-cell differentiation antigen CD6 (Itolizumab) is a ~71 kDa protein. Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex. Functions as a costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as a calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. 1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703 2. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938 3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806 4. Hassan, NJ. et al. (2006) Molecular and cellular biology 26, 6727-38. PMID: 16914752 5. Roncagalli, R. et al. (2014) Nature immunology 15, 384-392. PMID: 24584089 6. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728
Note	For Research Use Only.