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Anti-HeV/NiV Fusion Protein Antibody (DS90) (VK521063)

Anti-HeV/NiV Fusion Protein Antibody (DS90)
Anti-HeV/NiV Fusion Protein Antibody (DS90)
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Spec:
  • 50ug
  • 100ug
  • 1mg
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  • Datasheet

Overview
Catalog No.VK521063
Description
Anti-HeV/NiV Fusion Protein Antibody (DS90) [DS90] (VK521063) is a human monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, SPR, Neutralization. Suitable for Hendra virus and Nipah virus.
Highlights
  • Multi-Application — Validated across multiple applications.
Species reactivityHendra virus, Nipah virus
ApplicationsELISA, SPR, Neutralization
Host speciesHuman
IsotypeVHH-Fc
Clone IDDS90
Clonality Monoclonal
Target Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9IH63, O89342
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Fusion glycoprotein F0 (Fusion Protein) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

Note For research use only
Images
  • Anti-HeV/NiV Fusion Protein Antibody (DS90)

    SDS-PAGE

    SDS-PAGE for Anti-HeV/NiV Fusion Protein Antibody (DS90)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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