| Catalog No. | HY276016 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | IgG1-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, AFP, HPAFP |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P02771 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Background | Tacatuzumab is an anti-AFP (alpha-fetoprotein protein) human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
• If AFP is elevated, where is cancer? The case report on hereditary persistence of Alpha-fetoprotein., PMID:38125776
• Hereditary persistence of alpha-fetoprotein (HPAF P): review of the literature., PMID:21116028
• A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP)., PMID:7684942
• Hereditary persistence of alpha-fetoprotein., PMID:18985745
• Hereditary persistence of alpha-fetoprotein is due to both proximal and distal hepatocyte nuclear factor-1 site mutations., PMID:14699509
• [High alpha-fetoprotein persistence after orchiectomy. On a case of uncommon etiology]., PMID:21308671
• Hereditary persistence of alpha-fetoprotein. Case report and review of the literature., PMID:9681083
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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