Research Grade Anti-Human ENO1/Alpha-enolase (HuL001) (HY081016)

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100ug
1mg

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Overview

Catalog No.	HY081016
Description	Anti-Human ENO1/Alpha-enolase (HuL001) (HY081016) is a research-grade recombinant antibody targeting Non-neural enolase. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	HuL001
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Non-neural enolase, 2-phospho-D-glycerate hydro-lyase, MPB-1, ENO1, Plasminogen-binding protein, Enolase 1, C-myc promoter-binding protein, Alpha-enolase, MBP-1, MBPB1, MPB1, ENO1L1, NNE, Phosphopyruvate hydratase
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P06733
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	HuL001
Background	Alpha-enolase (ENO1) is a ~47 kDa protein. Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis. Also involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. 1. Sugahara, T. et al. (1992) Cytotechnology 10, 137-46. PMID: 1369209 2. Huang, H. et al. (2018) Molecular cell 70, 663-678.e6. PMID: 29775581 3. Feo, S. et al. (2000) FEBS letters 473, 47-52. PMID: 10802057 4. López-Alemany, R. et al. (2003) American journal of hematology 72, 234-42. PMID: 12666133 5. Ray, R. et al. (1991) Molecular and cellular biology 11, 2154-61. PMID: 2005901
Note	For research use only. Not suitable for clinical or therapeutic use.