| Catalog No. | HW564056 |
|---|
| Species reactivity | Human |
|---|
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
|---|
| Host species | Human |
|---|
| Isotype | IgG4-kappa |
|---|
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
P49961 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | 2643331-31-9 |
|---|
| Background | Eurestobart is a humanized IgG1κ antibody targeting ENTPDase.
• CD39 and CD73 in immunity and inflammation., PMID:23601906
• Ectonucleoside triphosphate diphosphohydrolase-1 (CD39) impacts TGF-β1 responses: insights into cardiac fibrosis and function following myocardial infarction., PMID:36240436
• Favorable function of Ectonucleoside triphosphate diphosphohydrolase 1 high expression in thyroid carcinoma., PMID:34465393
• Ectonucleoside triphosphate diphosphohydrolase-1 (E-NTPDase1/CD39) as a new prognostic marker in chronic lymphocytic leukemia., PMID:24684231
• Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells., PMID:37399271
• ATP signaling and NTPDase in Systemic Lupus Erythematosus (SLE)., PMID:30803848
• Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1)., PMID:14675084
• Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection., PMID:15852226
• CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury., PMID:17909107
• Ectonucleoside triphosphate diphosphohydrolase 1 and 5'-nucleotidase ecto gene polymorphisms and acute cellular rejection after liver transplantation., PMID:32248630
|
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| Note |
For research use only. Not suitable for clinical or therapeutic use. |
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